UPSC MainsANI-HUSB-VETER-SCIENCE-PAPER-I201110 Marks
Q6.

Write in brief about cardiac cycle.

How to Approach

This question requires a concise yet comprehensive explanation of the cardiac cycle. A structured approach is crucial. Begin with a definition of the cardiac cycle and its phases. Then, systematically describe each phase – atrial systole, ventricular systole (isovolumetric contraction, ejection), and ventricular diastole (isovolumetric relaxation, filling) – detailing the pressure and volume changes involved. Diagrams (which cannot be drawn here) would be incredibly helpful in visualizing the process. Finally, briefly mention the role of valves and the electrical conduction system.

Model Answer

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Introduction

The cardiac cycle is the sequence of coordinated events that occur during one complete heartbeat. It encompasses the contraction and relaxation of the heart chambers, resulting in the circulation of blood throughout the body. Understanding this cycle is fundamental to comprehending cardiovascular physiology and diagnosing various heart conditions. The average human heart beats approximately 60-100 times per minute, meaning a cardiac cycle repeats roughly 60-100 times per minute. This intricate process is tightly regulated by electrical signals and mechanical forces, ensuring efficient blood flow and maintaining systemic homeostasis.

What is the Cardiac Cycle?

The cardiac cycle is the complete sequence of events that occur during one heartbeat. It involves coordinated contraction (systole) and relaxation (diastole) of the atria and ventricles, facilitating the movement of blood through the heart and into circulation. The duration of the cardiac cycle is typically around 0.8 seconds in a normal adult at rest.

Phases of the Cardiac Cycle

The cardiac cycle can be divided into two main phases: diastole (relaxation and filling) and systole (contraction and ejection). Each phase is further subdivided into distinct stages.

1. Atrial Systole (0.1 seconds)

This phase begins with atrial contraction, pushing the remaining blood into the ventricles. It occurs just before ventricular systole. The atrioventricular (AV) valves (tricuspid and mitral) are open during this phase. The volume of blood transferred during atrial systole is called the atrial kick, contributing approximately 20% to the ventricular filling.

2. Ventricular Systole (0.3-0.4 seconds)

This phase is further divided into two stages:

  • Isovolumetric Contraction (0.04 seconds): Ventricular contraction begins, increasing pressure within the ventricles. Both AV valves (tricuspid and mitral) close, preventing backflow into the atria. During this brief period, the ventricular volume remains constant as the ventricles contract, but no blood is ejected.
  • Ventricular Ejection (0.26-0.36 seconds): As ventricular pressure exceeds the pressure in the aorta and pulmonary artery, the semilunar valves (aortic and pulmonary) open, and blood is ejected into the systemic and pulmonary circulations respectively. The amount of blood ejected with each beat is known as the stroke volume. A normal stroke volume is approximately 70 ml.

3. Ventricular Diastole (0.4-0.5 seconds)

This phase is also subdivided into two stages:

  • Isovolumetric Relaxation (0.04 seconds): Ventricular relaxation begins, causing a rapid decrease in ventricular pressure. The semilunar valves close, preventing backflow from the aorta and pulmonary artery. The ventricular volume remains constant during this phase.
  • Ventricular Filling (0.36-0.46 seconds): As ventricular pressure falls below the pressure in the atria, the AV valves open, and blood passively flows into the ventricles. Approximately 80% of ventricular filling occurs passively during this stage.
Phase Duration (seconds) Events
Atrial Systole 0.1 Atrial contraction, blood enters ventricles
Ventricular Systole 0.3-0.4 Isovolumetric contraction, ejection of blood
Ventricular Diastole 0.4-0.5 Isovolumetric relaxation, passive ventricular filling

Role of Valves and Conduction System

The cardiac cycle is precisely timed and coordinated by the electrical conduction system of the heart, which includes the sinoatrial (SA) node, atrioventricular (AV) node, bundle of His, and Purkinje fibers. The valves (AV and semilunar) ensure unidirectional blood flow, preventing backflow during diastole and systole respectively. The SA node initiates the heartbeat, setting the pace for the entire cycle.

Clinical Significance

Disruptions in the cardiac cycle can lead to various cardiovascular diseases, such as heart failure, arrhythmias, and valvular heart disease. Understanding the cardiac cycle is crucial for diagnosing and managing these conditions effectively.

Conclusion

The cardiac cycle is a complex and meticulously coordinated sequence of events essential for life. It involves the rhythmic contraction and relaxation of the heart chambers, driven by electrical impulses and regulated by the precise opening and closing of heart valves. A thorough understanding of this cycle is vital for healthcare professionals and provides valuable insight into the intricate workings of the cardiovascular system. Further research continues to refine our understanding of the cardiac cycle and its role in overall health.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Stroke Volume
The volume of blood ejected from the heart with each beat. A normal stroke volume is approximately 70 ml.
Atrial Kick
The additional blood volume transferred into the ventricles during atrial systole, contributing approximately 20% to ventricular filling.

Key Statistics

The average resting heart rate is 60-100 beats per minute.

Source: American Heart Association

The cardiac cycle duration is approximately 0.8 seconds in a normal adult at rest.

Source: Physiology Textbooks

Examples

Valvular Heart Disease

Conditions like mitral valve stenosis disrupt the normal flow of blood through the heart, impacting the cardiac cycle and leading to symptoms like shortness of breath and fatigue.

Arrhythmias

Irregular heart rhythms, such as atrial fibrillation, can significantly alter the timing and coordination of the cardiac cycle, reducing the heart's efficiency.

Frequently Asked Questions

What is the difference between systole and diastole?

Systole refers to the contraction phase of the heart, while diastole refers to the relaxation phase. Both are essential for proper blood circulation.

How is the cardiac cycle regulated?

The cardiac cycle is regulated by the electrical conduction system, hormones (like adrenaline), and the autonomic nervous system.

Topics Covered

Animal PhysiologyCardiovascular SystemHeart FunctionBlood CirculationCardiac Events