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Q7.

Why RABIES in humans is also called HYDROPHOBIA ? Explain the reasons for recent high incidence of deaths due to RABIES in Humans in India.

How to Approach

This question requires a two-pronged approach. First, explain the etymology of hydrophobia and the physiological reasons behind it. Second, analyze the recent surge in rabies deaths in India, considering factors like inadequate vaccination coverage in animals, lack of awareness, and challenges in healthcare access. The answer should be structured into these two parts, followed by a discussion of potential solutions and preventative measures. A table summarizing the contributing factors to the recent surge will enhance clarity.

Model Answer

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Introduction

Rabies, a neglected tropical disease, remains a significant public health concern globally, particularly in developing nations. Characterized by a tragic and invariably fatal outcome, rabies is transmitted through the saliva of infected animals, primarily dogs. The term "hydrophobia," derived from the Greek words "hydro" (water) and "phobos" (fear), is uniquely associated with human rabies, reflecting the agonizing symptom of fear of water that often manifests during the disease’s progression. India, despite significant efforts, continues to bear a disproportionate burden of rabies deaths, a situation demanding urgent attention and a multi-faceted response. Recent years have witnessed a concerning spike in fatalities, prompting a critical examination of the underlying causes.

Why Rabies in Humans is Called Hydrophobia

The term "hydrophobia" is a misnomer, as patients do not inherently fear water. It arises from a specific neurological manifestation during the furious form of rabies. The rabies virus, after entering the body, travels to the brain and affects the cranial nerves, particularly the pharyngeal and laryngeal muscles. This leads to intense pain and spasms when attempting to swallow, even a small amount of water, triggering a reflexive aversion. The patient experiences excruciating discomfort and a feeling of suffocation, which is misinterpreted as a fear of water. The patient's distress and involuntary muscle contractions often create the illusion of a phobia, hence the name.

Physiological Basis of Hydrophobia

The physiological mechanism involves the following:

  • Viral Replication: The rabies virus replicates in the salivary glands and then ascends to the brain.
  • Cranial Nerve Involvement: The virus affects the glossopharyngeal and vagus nerves, which control swallowing.
  • Spasm and Pain: Attempting to swallow triggers painful spasms in the throat muscles.
  • Reflexive Aversion: The pain and discomfort lead to a reflexive aversion to swallowing, which is observed as hydrophobia.

Reasons for Recent High Incidence of Deaths Due to Rabies in India

Despite the availability of pre- and post-exposure prophylaxis (PEP), India accounts for approximately 55% of global rabies deaths annually. Several factors contribute to this alarming situation:

1. Inadequate Animal Vaccination Coverage

The National Rabies Control Programme (NRCP) was launched in 2005, aiming for 70% dog vaccination coverage. However, this target has rarely been achieved consistently across all regions.

  • Lack of Resources: Limited funding and logistical challenges hinder widespread vaccination efforts.
  • Urban-Rural Disparity: Vaccination coverage is significantly lower in rural areas due to accessibility issues and lower awareness.
  • Stray Dog Population: A large, uncontrolled stray dog population acts as a primary reservoir for the virus.

2. Delayed and Inadequate Post-Exposure Prophylaxis (PEP)

PEP is highly effective if administered promptly after exposure. However, several barriers prevent timely access:

  • Geographical Barriers: Remote areas lack access to healthcare facilities offering PEP.
  • Lack of Awareness: Many people are unaware of the risk of rabies or the importance of seeking PEP.
  • Cost: While PEP is subsidized, the cost can still be a deterrent for some.
  • Misconceptions: Traditional beliefs and superstitions often delay seeking medical attention.

3. Lack of Awareness and Public Education

Insufficient public awareness campaigns fail to educate people about rabies prevention, transmission, and the importance of PEP.

  • Misinformation: False beliefs about rabies transmission persist, leading to inappropriate and ineffective prevention strategies.
  • Limited Outreach: Awareness programs often fail to reach vulnerable populations in rural areas.

4. Challenges in Healthcare Infrastructure and Human Resources

Weak healthcare infrastructure and a shortage of trained medical personnel further exacerbate the problem.

  • Limited Diagnostic Capabilities: Lack of reliable diagnostic facilities delays confirmation of rabies cases.
  • Insufficient Trained Personnel: Few healthcare professionals are adequately trained in rabies diagnosis and management.
Factor Description
Animal Vaccination Low vaccination coverage, particularly in rural areas.
PEP Access Delayed or unavailable PEP due to geographical barriers, cost, and awareness.
Public Awareness Limited understanding of rabies transmission and prevention.
Healthcare Infrastructure Weak infrastructure and shortage of trained personnel.

Government Initiatives and Potential Solutions

The government is implementing various measures to combat rabies, including:

  • National Rabies Control Programme (NRCP): Continued efforts to increase dog vaccination coverage.
  • Mass Rabies Vaccination Campaigns: Periodic campaigns to vaccinate stray dogs.
  • Strengthening PEP Delivery: Establishing more PEP centers and ensuring accessibility.
  • Public Awareness Campaigns: Disseminating information about rabies prevention through various channels.
  • One Health Approach: Recognizing the interconnectedness of animal, human, and environmental health.

Conclusion

The persistence of rabies as a major public health problem in India underscores the urgent need for a comprehensive and sustained response. Addressing the multifaceted challenges, including inadequate animal vaccination, delayed PEP, and lack of awareness, requires a concerted effort involving government agencies, healthcare professionals, and the community. Strengthening the NRCP, improving healthcare access, and promoting public education are crucial steps towards eliminating rabies and protecting vulnerable populations. A "One Health" approach, recognizing the interconnectedness of animal and human health, is paramount for long-term success.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Hydrophobia
A misnomer referring to the difficulty and pain experienced when swallowing during rabies infection, not a fear of water.
PEP (Post-Exposure Prophylaxis)
A series of vaccinations given after potential exposure to rabies virus to prevent infection.

Key Statistics

India accounts for approximately 55% of global rabies deaths annually.

Source: World Health Organization (WHO) estimates

The National Rabies Control Programme (NRCP) aimed for 70% dog vaccination coverage, a target rarely achieved.

Source: NRCP Annual Reports

Examples

Kerala's Rabies Control Program

Kerala has implemented a successful program focused on mass dog vaccination and public awareness, resulting in significantly lower rabies incidence compared to other states.

Uttar Pradesh Case Study

UP, with a large dog population and limited resources, faces significant challenges in rabies control, highlighting the need for targeted interventions and increased funding.

Frequently Asked Questions

What is the effectiveness of PEP?

PEP is almost 100% effective if administered promptly after exposure.

Can rabies be cured once symptoms appear?

Unfortunately, there is no cure for rabies once symptoms manifest. The disease is invariably fatal.

Topics Covered

HealthScience and TechnologyZoonotic DiseasesPublic HealthEpidemiology