UPSC MainsZOOLOGY-PAPER-II201315 Marks
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Q11.

Which eukaryotes do not contain repetitive DNA? Give a brief account of biological macromolecules found in all living organisms.

How to Approach

This question requires a two-pronged answer. First, identify eukaryotes lacking repetitive DNA, which demands knowledge of genome composition across different eukaryotic groups. Second, a detailed account of biological macromolecules – carbohydrates, lipids, proteins, and nucleic acids – their structures, functions, and significance in all living organisms is needed. The answer should be structured to address each part separately, providing specific examples and emphasizing the universality of macromolecules.

Model Answer

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Introduction

The eukaryotic genome is characterized by a complex organization, often including substantial amounts of non-coding repetitive DNA. However, not all eukaryotes exhibit this feature to the same extent. Biological macromolecules are the building blocks of life, essential for structure, function, and information storage in all organisms, from bacteria to humans. These macromolecules – carbohydrates, lipids, proteins, and nucleic acids – share a common foundation in carbon chemistry and are crucial for maintaining life processes. Understanding their composition and roles is fundamental to comprehending biological systems.

Eukaryotes Lacking Repetitive DNA

While most eukaryotes possess repetitive DNA sequences, certain groups exhibit relatively low levels of such sequences. These include:

  • Dinoflagellates: These unicellular algae have remarkably small genomes with a very low proportion of repetitive DNA. Their genomes are often highly condensed and lack the extensive non-coding regions found in many other eukaryotes.
  • Microsporidia: These obligate intracellular parasites have extremely reduced genomes, often containing minimal repetitive DNA due to their parasitic lifestyle and reliance on the host cell machinery.
  • Some Fungi: Certain fungal species, particularly those with streamlined genomes adapted to specific ecological niches, exhibit lower levels of repetitive DNA compared to others.
  • Certain Protists: Some protists, particularly those with relatively simple lifestyles, have genomes with a lower proportion of repetitive DNA.

The reduction in repetitive DNA is often linked to genome streamlining, a process where non-essential DNA is lost during evolution, particularly in organisms with rapid reproductive rates or parasitic lifestyles.

Biological Macromolecules Found in All Living Organisms

1. Carbohydrates

Carbohydrates are primarily composed of carbon, hydrogen, and oxygen in a ratio of 1:2:1. They serve as a primary source of energy and structural components.

  • Monosaccharides: Simple sugars like glucose, fructose, and galactose.
  • Disaccharides: Formed by the joining of two monosaccharides (e.g., sucrose, lactose).
  • Polysaccharides: Complex carbohydrates like starch (energy storage in plants), glycogen (energy storage in animals), and cellulose (structural component of plant cell walls).

2. Lipids

Lipids are hydrophobic molecules composed of carbon, hydrogen, and oxygen, but with a much lower proportion of oxygen compared to carbohydrates. They are crucial for energy storage, cell membrane structure, and signaling.

  • Triglycerides: Composed of glycerol and three fatty acids; used for long-term energy storage.
  • Phospholipids: Major component of cell membranes, forming a bilayer structure.
  • Steroids: Characterized by a four-ring structure (e.g., cholesterol, hormones like testosterone and estrogen).

3. Proteins

Proteins are complex macromolecules composed of amino acids linked by peptide bonds. They perform a vast array of functions, including enzymatic catalysis, structural support, transport, and immune defense.

  • Amino Acids: The building blocks of proteins; 20 standard amino acids are found in proteins.
  • Protein Structure: Primary (amino acid sequence), Secondary (alpha-helices and beta-sheets), Tertiary (3D folding), and Quaternary (multiple polypeptide chains).
  • Enzymes: Biological catalysts that speed up chemical reactions.

4. Nucleic Acids

Nucleic acids – DNA and RNA – are responsible for storing and transmitting genetic information. They are composed of nucleotides.

  • DNA (Deoxyribonucleic Acid): Contains the genetic code; double-stranded helix structure.
  • RNA (Ribonucleic Acid): Involved in protein synthesis; single-stranded structure. Types include mRNA, tRNA, and rRNA.
  • Nucleotides: Composed of a sugar (deoxyribose in DNA, ribose in RNA), a phosphate group, and a nitrogenous base (adenine, guanine, cytosine, thymine in DNA; uracil replaces thymine in RNA).
Macromolecule Monomer Function
Carbohydrates Monosaccharides Energy source, structural support
Lipids Fatty acids, glycerol Energy storage, cell membrane structure
Proteins Amino acids Enzymatic catalysis, structural support, transport
Nucleic Acids Nucleotides Genetic information storage and transmission

Conclusion

In conclusion, while repetitive DNA is common in many eukaryotes, certain groups like dinoflagellates and microsporidia exhibit streamlined genomes with minimal repetitive sequences. All living organisms rely on the four major classes of biological macromolecules – carbohydrates, lipids, proteins, and nucleic acids – for their structure, function, and information storage. These macromolecules, built from their respective monomers, are universally essential for life and demonstrate the fundamental unity of biological systems. Further research into genome streamlining and macromolecular interactions continues to refine our understanding of life's complexities.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Genome streamlining
Genome streamlining refers to the reduction in genome size through the loss of non-essential DNA sequences, often observed in organisms with rapid reproduction rates or parasitic lifestyles.
Polymorphism
Polymorphism refers to the occurrence of multiple forms of a gene or DNA sequence within a population, contributing to genetic diversity.

Key Statistics

The human genome is estimated to be only about 1.5% coding DNA, with the remaining 98.5% being non-coding DNA, much of which is repetitive. (Source: ENCODE Project, 2012)

Source: ENCODE Project Consortium (2012)

Approximately 50% of the human genome is composed of transposable elements, a type of repetitive DNA. (Source: International Human Genome Sequencing Consortium, 2003)

Source: International Human Genome Sequencing Consortium (2003)

Examples

Prasinophytes

Prasinophytes, a group of unicellular green algae, possess some of the smallest known eukaryotic genomes, with a very low proportion of repetitive DNA, demonstrating efficient genome organization.

Frequently Asked Questions

What is the role of non-repetitive DNA?

Non-repetitive DNA contains genes that code for proteins and regulatory sequences that control gene expression. It is essential for the organism's function and development.

Topics Covered

BiologyBiochemistryMolecular BiologyMacromoleculesGenetics