UPSC MainsANI-HUSB-VETER-SCIENCE-PAPER-I201525 Marks
Q13.

Enumerate the water-soluble vitamins. Write the coenzymes or prosthetic groups and enzymic or other functions of B vitamins. Write the functions and deficiency symptoms of vitamin E in poultry.

How to Approach

This question requires a structured response covering water-soluble vitamins, their coenzymes/prosthetic groups, functions, and deficiency symptoms, specifically focusing on B vitamins and Vitamin E in poultry. I will begin by defining water-soluble vitamins and listing them. Then, I’ll address each B vitamin individually, detailing its role and deficiency effects. Finally, I'll discuss Vitamin E, its functions, and deficiency symptoms in poultry, using a tabular format for clarity. A concise conclusion will summarize the key points.

Model Answer

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Introduction

Vitamins are organic compounds required in small amounts for normal physiological functions. They are broadly classified into fat-soluble (A, D, E, K) and water-soluble vitamins (B vitamins and Vitamin C). Water-soluble vitamins are generally not stored in the body to a significant extent and need to be regularly replenished through diet. The B vitamins, a complex group, play crucial roles as coenzymes in various metabolic pathways. Understanding their functions and deficiencies is vital, particularly in livestock farming like poultry, where nutritional deficiencies can severely impact productivity and health.

Water-Soluble Vitamins

Water-soluble vitamins include Vitamin C and the B vitamins: Thiamin (B1), Riboflavin (B2), Niacin (B3), Pantothenic acid (B5), Pyridoxine (B6), Biotin (B7), Folate (B9), and Cobalamin (B12). Unlike fat-soluble vitamins, these are readily excreted and require regular intake.

B Vitamins: Coenzymes, Functions, and Deficiencies

The B vitamins act primarily as coenzymes, assisting enzymes in catalyzing biochemical reactions. Here's a breakdown of each:

Thiamin (B1)

  • Coenzyme: Thiamine pyrophosphate (TPP)
  • Function: Carbohydrate metabolism, nerve function.
  • Deficiency: Beriberi (in humans), neurological issues, poor growth in poultry.

Riboflavin (B2)

  • Coenzyme: Flavin adenine dinucleotide (FAD), Flavin mononucleotide (FMN)
  • Function: Energy production, cellular growth, antioxidant defense.
  • Deficiency: Ariboflavinosis (in humans), skin lesions, mouth sores, reduced growth and egg production in poultry.

Niacin (B3)

  • Coenzyme: Nicotinamide adenine dinucleotide (NAD), Nicotinamide adenine dinucleotide phosphate (NADP)
  • Function: Energy metabolism, DNA repair, cell signaling.
  • Deficiency: Pellagra (in humans), diarrhea, dermatitis, dementia, poor hatchability in poultry.

Pantothenic Acid (B5)

  • Coenzyme: Coenzyme A (CoA)
  • Function: Fatty acid synthesis, carbohydrate metabolism, protein synthesis.
  • Deficiency: Rare, but can cause neurological problems and impaired growth.

Pyridoxine (B6)

  • Coenzyme: Pyridoxal phosphate (PLP)
  • Function: Amino acid metabolism, neurotransmitter synthesis, heme synthesis.
  • Deficiency: Neurological problems, skin disorders, anemia.

Biotin (B7)

  • Coenzyme: Biotinyl-adenine monophosphate (BAM)
  • Function: Carboxylation reactions (fatty acid synthesis, gluconeogenesis).
  • Deficiency: Rare, but can cause skin problems and neurological symptoms.

Folate (B9)

  • Coenzyme: Tetrahydrofolate (THF)
  • Function: DNA synthesis, cell division, amino acid metabolism.
  • Deficiency: Megaloblastic anemia, neural tube defects (in humans), reduced egg production and hatchability in poultry.

Cobalamin (B12)

  • Coenzyme: 5'-Deoxyadenosylcobalamin, Methylcobalamin
  • Function: DNA synthesis, nerve function, red blood cell formation.
  • Deficiency: Pernicious anemia, neurological problems. Poultry are often deficient, requiring supplementation.

Vitamin E in Poultry: Functions and Deficiency Symptoms

Vitamin E, a fat-soluble vitamin, is crucial for poultry health, acting as an antioxidant protecting cell membranes from damage. Deficiency is relatively common, especially in rapidly growing birds.

Function Deficiency Symptoms Severity
Antioxidant: Protects cell membranes from oxidative damage Muscular dystrophy (white stripping disease) – particularly in chicks Severe: High mortality
Immune Function: Supports immune system development Hemorrhagic lesions, especially in the thigh muscles Moderate: Reduced growth and immunity
Reproductive Health: Essential for fertility Reduced hatchability, poor chick quality Mild to Moderate: Impacts breeding performance
Vitamin A absorption: Helps in the absorption of Vitamin A Impaired vision, reduced growth Mild

The susceptibility to Vitamin E deficiency is heightened in rapidly growing broiler chickens and those raised on diets low in Vitamin E. Selenium deficiency can exacerbate Vitamin E deficiency, as selenium is a cofactor for glutathione peroxidase, another important antioxidant enzyme.


Conclusion

In conclusion, water-soluble vitamins, particularly the B vitamins, are vital coenzymes involved in a multitude of metabolic processes. Understanding their individual roles and deficiency symptoms is crucial for maintaining optimal health and productivity, especially in poultry farming. Vitamin E, a fat-soluble vitamin, is equally important for poultry, acting as a critical antioxidant. Addressing nutritional deficiencies through balanced diets and supplementation is paramount for ensuring healthy growth, reproduction, and overall well-being in livestock.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Coenzyme
An organic non-protein compound that binds to an enzyme to aid in its function. Many vitamins act as coenzymes.
Prosthetic Group
A non-protein component tightly bound to an enzyme, essential for its catalytic activity. Similar to a coenzyme, but typically part of the enzyme structure.

Key Statistics

Globally, Vitamin A deficiency affects approximately 25% of children under 5 (WHO, 2023). While not directly addressed in the question, it highlights the broader importance of micronutrient deficiencies.

Source: World Health Organization

Poultry diets often require Vitamin E supplementation, with recommended levels ranging from 10-30 IU/kg of feed, depending on the breed and production system.

Source: Poultry Science Association

Examples

Beriberi

A disease caused by thiamin (B1) deficiency, historically prevalent in regions where polished rice (low in thiamin) was a primary food source.

White Stripping Disease

A severe Vitamin E deficiency in young chicks, characterized by hemorrhages in the thigh muscles due to muscle degeneration.

Frequently Asked Questions

Why are water-soluble vitamins not stored in the body?

Because the body can readily excrete excess amounts through urine. This necessitates regular dietary intake to prevent deficiencies.

Can B vitamin deficiencies occur in developed countries?

Yes, they can. Factors like restrictive diets, alcoholism, and certain medications can interfere with B vitamin absorption and utilization.

Topics Covered

BiologyAnimal ScienceNutritionPoultry FarmingVitamins