UPSC Mains MEDICAL-SCIENCE-PAPER-I 2015

Describe stomach under the following headings : (i) Location (ii) External features (iii) Arterial supply (iv) Clinical anatomy

Give the sequence of events that occurs during transmission of nerve impulse through neuromuscular junction.

Differentiate between isometric and isotonic contraction in skeletal muscle. Give one example of each type.

Describe the cervical part of the sympathetic chain.

Define 'clearance' of a substance by kidneys. Which clearance tests provide an estimate of glomerular filtration rate (GFR)? Explain which of these is the test of choice for assessment of GFR. What is eGFR?

What are the main important functions of pyridoxine (vitamin B6)? Explain.

What are the features of innate and acquired immunity? What is the mechanism of action of immunoglobulins?

Describe the projection fibres of cerebrum.

Define 'cardiac output' and 'cardiac index'. Describe the regulation of cardiac output in the body.

Describe in detail about the origin and distribution of the sciatic nerve. Add a note on its clinical importance.

Vitamin D resistant rickets

Chromium as a trace element

Role of plasma enzymes in evaluation of liver function

Describe tongue under the following subheadings : (i) Mucous membrane and its nerve supply (ii) Muscles, movements produced by them and their nerve supply (iii) Lymphatic drainage (iv) Clinical anatomy

Name the hormones involved in the regulation of blood glucose level. Discuss the pathophysiology of diabetes mellitus.

Enumerate the hormones of posterior pituitary gland and describe their actions in the body.

Define and classify hypersensitivity. Describe type I hypersensitivity.

Discuss the pharmacotherapy of gout. Describe the rationale of the use of colchicine during acute attack of gout.

Enumerate the major etiological factors associated with carcinoma of lung. Give the gross, microscopic features and spread of squamous cell carcinoma lung.

A young person of 25 years has sustained smooth barrel shotgun firearm injury on right side of chest. How will you establish on clinical examination the entry wound and distance of fire?

Give etiopathogenesis of carcinoma cervix. What are the tests employed for diagnosis of carcinoma cervix? Give the stages of carcinoma cervix.

Discuss the pharmacology of calcium channel blockers. Enumerate the reasons for combining beta blockers with amlodipine.

Discuss morphology and antigenic types of dengue virus. Describe the clinical manifestations and laboratory diagnosis of dengue fever.

Write hypothetical medicolegal report of an injured person having sustained stab wound penetrating lung deep on right side of chest.