UPSC MainsMEDICAL-SCIENCE-PAPER-II20164 Marks
Q21.

Define a non-infective and a parasitic, infective dermatosis.

How to Approach

This question requires defining two distinct types of dermatoses: non-infective and parasitic infective. The approach should be to first define dermatosis generally, then clearly differentiate between the two categories, providing examples for each. Focus on etiology, transmission (or lack thereof), and characteristic features. A concise and precise answer is expected, demonstrating understanding of dermatological classifications. Structure the answer by defining dermatosis, then defining and exemplifying non-infective dermatosis, followed by parasitic infective dermatosis.

Model Answer

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Introduction

Dermatosis refers to any disease of the skin. These conditions are incredibly diverse, ranging from common acne to life-threatening skin cancers. They can be broadly categorized based on their etiology, with infectious and non-infectious causes being primary distinctions. Within infectious dermatoses, parasitic infections represent a significant subset. Understanding these classifications is crucial for accurate diagnosis and appropriate management. This answer will define a non-infective and a parasitic, infective dermatosis, highlighting their key characteristics and providing illustrative examples.

Non-Infective Dermatosis

Non-infective dermatoses are skin conditions that are not caused by infectious agents like bacteria, viruses, fungi, or parasites. Their etiology is often multifactorial, involving genetic predisposition, immune dysregulation, environmental factors, or unknown causes. They are not transmissible from person to person.

  • Etiology: Genetic, autoimmune, allergic, idiopathic.
  • Transmission: Non-contagious.
  • Examples:
    • Atopic Dermatitis (Eczema): A chronic inflammatory skin condition characterized by itchy, red, and inflamed skin. Often associated with a family history of allergies or asthma.
    • Psoriasis: An autoimmune condition causing raised, red, scaly patches on the skin. Genetic factors play a significant role.
    • Lichen Planus: An inflammatory condition affecting skin, mucous membranes, hair, and nails. The cause is unknown, but it's thought to be immune-mediated.

Parasitic Infective Dermatosis

Parasitic infective dermatoses are skin conditions caused by organisms that live on or within the skin, obtaining nourishment from the host. These are infectious, meaning they can be transmitted from one individual to another, although the mode of transmission varies depending on the parasite.

  • Etiology: Infestation with ectoparasites (living on the skin) or endoparasites (living within the skin).
  • Transmission: Direct contact, vector-borne, or through contaminated materials.
  • Examples:
    • Scabies: Caused by the mite Sarcoptes scabiei, which burrows into the skin, causing intense itching, especially at night. Highly contagious through close skin-to-skin contact.
    • Pediculosis (Lice): Infestation with lice (head lice, body lice, pubic lice). Transmitted through direct contact or sharing of personal items.
    • Cutaneous Larva Migrans (Creeping Eruption): Caused by larvae of hookworms that penetrate the skin, leaving itchy, winding tracks. Acquired through contact with contaminated soil or sand.

The following table summarizes the key differences:

Feature Non-Infective Dermatosis Parasitic Infective Dermatosis
Etiology Genetic, autoimmune, allergic, idiopathic Parasitic infestation
Infectious? No Yes
Transmission Non-contagious Direct contact, vector-borne, contaminated materials
Example Psoriasis Scabies

Conclusion

In conclusion, dermatoses encompass a wide spectrum of skin conditions. Non-infective dermatoses arise from internal factors and are not transmissible, while parasitic infective dermatoses are caused by external organisms and can spread between individuals. Accurate differentiation between these categories is paramount for effective diagnosis, treatment, and public health measures. Further research into the underlying mechanisms of both types of dermatoses is crucial for developing novel therapeutic strategies and improving patient outcomes.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Dermatosis
Any disease of the skin. It is a general term encompassing a wide range of conditions, from common rashes to serious systemic diseases manifesting in the skin.
Ectoparasite
A parasite that lives on the outer surface of a host, such as the skin, fur, or feathers. Examples include lice, mites, and ticks.

Key Statistics

Globally, skin diseases are estimated to affect approximately 900 million people, representing around 13% of the global burden of disease. (Source: WHO, 2023 - knowledge cutoff)

Source: World Health Organization (WHO)

Scabies affects an estimated 300 million people worldwide annually, particularly in resource-limited settings. (Source: CDC, 2022 - knowledge cutoff)

Source: Centers for Disease Control and Prevention (CDC)

Examples

Vitiligo

Vitiligo is a non-infective dermatosis characterized by loss of skin pigmentation, resulting in white patches. It is an autoimmune condition where the body's immune system attacks melanocytes (pigment-producing cells).

Frequently Asked Questions

Can stress worsen dermatological conditions?

Yes, stress is a known trigger or exacerbating factor for many dermatological conditions, including psoriasis, eczema, and urticaria. The neuroimmune connection plays a significant role.

Topics Covered

MedicineDermatologySkin DiseasesInfectionsParasitesDermatology