UPSC MainsMEDICAL-SCIENCE-PAPER-II20172 Marks
Q8.

Enlist the vaccines which can reduce the incidence of Acute Respiratory Infection in children.

How to Approach

This question requires a direct and concise answer listing vaccines effective against Acute Respiratory Infections (ARIs) in children. The approach should be to categorize vaccines based on the specific ARIs they prevent (e.g., influenza, pneumococcal disease, pertussis, measles). Mentioning the target age groups for vaccination is also crucial. The answer should be structured as a list, potentially using a table for clarity. Focus on vaccines commonly included in national immunization programs.

Model Answer

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Introduction

Acute Respiratory Infections (ARIs) are a leading cause of morbidity and mortality in children under five years of age globally, and particularly in developing countries. These infections range from mild common colds to severe pneumonia and bronchiolitis. Vaccination remains one of the most effective strategies for preventing ARIs and reducing their associated burden. Several vaccines can significantly reduce the incidence and severity of ARIs in children, protecting them from potentially life-threatening complications. This answer will enumerate the key vaccines used to combat ARIs in pediatric populations.

Vaccines Reducing Incidence of Acute Respiratory Infections in Children

The following vaccines are crucial in reducing the incidence of ARIs in children:

  • Influenza Vaccine: Annual influenza vaccination is recommended for children 6 months and older. It protects against influenza viruses (types A and B), which are common causes of ARIs, particularly during seasonal outbreaks.
  • Pneumococcal Conjugate Vaccine (PCV): PCV protects against Streptococcus pneumoniae, a major cause of pneumonia, otitis media (middle ear infection), and meningitis. Different serotypes are covered by different PCV formulations (PCV10, PCV13, PCV15, PCV20). Typically administered in infancy as a series of doses.
  • Haemophilus influenzae type b (Hib) Vaccine: Hib vaccine protects against Hib bacteria, which can cause pneumonia, meningitis, and epiglottitis. It’s usually given as part of routine childhood immunization.
  • Pertussis (Whooping Cough) Vaccine: Pertussis is a highly contagious bacterial infection that causes severe coughing. The DTwP (Diphtheria, Tetanus, and whole-cell Pertussis) or DTaP (Diphtheria, Tetanus, and acellular Pertussis) vaccine is given in infancy and booster doses are recommended.
  • Measles Vaccine: Measles can lead to severe pneumonia, especially in malnourished children. The measles vaccine is typically given as part of the MMR (Measles, Mumps, and Rubella) vaccine.
  • Varicella (Chickenpox) Vaccine: While primarily known for preventing chickenpox, varicella can sometimes lead to secondary bacterial pneumonia. Vaccination reduces the risk of both primary varicella and its complications.
  • Respiratory Syncytial Virus (RSV) Vaccine: Recently, RSV vaccines have been approved for maternal immunization (to protect infants) and for older adults. These vaccines are a significant advancement in preventing severe RSV-related ARIs, particularly bronchiolitis and pneumonia in infants. (Approved in 2023)

Vaccine Schedule & Considerations

The specific schedule and type of vaccine used may vary depending on national immunization programs and local epidemiology. It's crucial to adhere to recommended vaccination schedules to ensure optimal protection.

Vaccine Target Age Protection Against
Influenza 6 months + (annually) Influenza A & B
PCV Infancy (series of doses) Streptococcus pneumoniae
Hib Infancy (series of doses) Haemophilus influenzae type b
DTaP/DTwP Infancy (series of doses + boosters) Pertussis
MMR 12-15 months (2 doses) Measles
Varicella 12-15 months (2 doses) Varicella-Zoster Virus
RSV Maternal (28-36 weeks gestation) & Older Adults Respiratory Syncytial Virus

Conclusion

Vaccination is a cornerstone of preventing ARIs in children. By utilizing vaccines against influenza, pneumococcus, Hib, pertussis, measles, varicella, and now RSV, we can significantly reduce the incidence, severity, and associated mortality of these infections. Continued efforts to improve vaccine coverage, develop new vaccines, and address vaccine hesitancy are essential for protecting children's health and well-being. The recent approval of RSV vaccines represents a major step forward in combating a significant cause of infant respiratory illness.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Herd Immunity
Herd immunity occurs when a large portion of a community becomes immune to a disease, making the spread of disease from person to person unlikely. Vaccination is a key strategy for achieving herd immunity.

Key Statistics

According to WHO, ARIs are responsible for approximately 2.6 million deaths annually, with the majority occurring in children under five years of age. (Data as of 2019, pre-pandemic)

Source: World Health Organization (WHO)

Globally, influenza is estimated to cause 290,000 to 650,000 respiratory deaths annually. (CDC estimates, 2017-2018)

Source: Centers for Disease Control and Prevention (CDC)

Examples

Pneumococcal Conjugate Vaccine Impact in Gambia

The introduction of PCV in Gambia in 2009 led to a dramatic reduction in pneumococcal pneumonia and overall childhood mortality. Studies showed a 70% reduction in pneumococcal disease cases within the first five years of implementation.

Frequently Asked Questions

Can vaccines completely eliminate the risk of ARIs?

No, vaccines do not provide 100% protection. However, they significantly reduce the risk of contracting the infection, and even if a vaccinated child does get sick, the illness is usually milder and less likely to lead to serious complications.

Topics Covered

MedicinePediatricsImmunologyVaccinesARIPreventionChild Health