UPSC Mains MEDICAL-SCIENCE-PAPER-I 2018

Discuss the Functional components, Nucleus, course and distribution of 4th cranial nerve. Add a note on its clinical significance.

What are extra pyramidal tracts? Describe their functions. How do they differ from pyramidal tracts?

What is the regulatory mechanism of iron absorption at the level of intestine? What is the role of TIBC in iron metabolism? How does the body conserve iron?

Classify Arches of foot. Write in details about medial longitudinal Arch.

Give an account of characteristics of a hormone. Describe the hormonal regulation of calcium level in the blood.

Describe Hip Joint under the following headings: Articular surface and Types Ligaments Relations Blood supply and Nerve supply Movement

Explain regulation of megakaryocytopoiesis.

Define the term "cardiac reserve". Explain how is its control governed?

Describe briefly:

Role of PCR (Polymerase Chain Reaction) in the diagnosis and management of Mycobacterium tuberculosis.

Role of iodine in synthesis and function of thyroid hormone. What is Graves Disease?

Explain the changes which takes place during luteal phase of menstrual cycle.

What are modes of contraction in a skeletal muscle? Give suitable examples. Explain length-tension relationship in skeletal muscle.

Describe the principle of Radio Immuno Assay (RIA). What are the main advantages and disadvantages of RIA technique.

What is folate trap? What are the methods of assessment of vitamin B12 deficiency.

Describe the External, Internal features, parts of cerebellum. Add a note on the constitution of cerebellar peduncles.

Define impaired glucose tolerance. Discuss the pathogenesis of Type I diabetes mellitus.

Discuss the strategic plans laid down by NACO for diagnosis of individuals with AIDS indicative disease symptoms.

Discuss pathogenesis and laboratory diagnosis of Dengue haemorrhagic fever.

Discuss the adverse effects associated with the use of antimicrobial agents.

Describe risk factors identified for breast carcinoma.

Discuss molecular subtypes of invasive breast carcinoma.

Define 'Head Injury'. What is the mechanism of 'Coup' and 'Contre Coup' brain damage.

Discuss briefly the formula used for calculating the 'Total Body Surface Area' involved in burns in an adult and a child.