UPSC MainsANI-HUSB-VETER-SCIENCE-PAPER-I202210 Marks150 Words
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Q5.

Define inbreeding and describe the different genetic and phenotypic consequences of inbreeding.

How to Approach

This question requires a clear and concise explanation of inbreeding and its consequences. The approach should be to first define inbreeding, then elaborate on both genetic and phenotypic consequences, categorizing them for clarity. Use of examples will enhance understanding. Structure the answer around a definition, followed by genetic and phenotypic consequences, and conclude with a summary emphasizing the need for careful breeding practices. A table comparing the effects could be beneficial.

Model Answer

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Introduction

Inbreeding, a common practice in animal breeding, refers to the mating of individuals closely related by descent. While historically used to fix desirable traits, it’s a subject of careful consideration in modern animal husbandry due to its potential drawbacks. The National Dairy Development Board (NDDB) constantly monitors and advises on breeding programs to minimize deleterious effects. Understanding the genetic and phenotypic consequences of inbreeding is crucial for ensuring the health, productivity, and genetic diversity of livestock populations. This response will define inbreeding and detail its consequences.

Definition of Inbreeding

Inbreeding is the process of mating individuals within a closely related population or lineage. This can involve siblings, parent-offspring, or cousins. The inbreeding coefficient (F) quantifies the probability that an allele in an individual is inherited from both parents who are related. A coefficient of F=0 signifies no relationship, while F=1 indicates that both parents are identical.

Genetic Consequences of Inbreeding

The primary genetic consequence of inbreeding is the increased expression of recessive alleles. Most organisms carry some deleterious recessive genes. In unrelated individuals, these genes are likely to be masked by dominant alleles. However, inbreeding increases the probability of these recessive alleles being homozygous, leading to their manifestation.

  • Homozygosity Increase: Inbreeding drastically increases the proportion of homozygous gene pairs.
  • Recessive Allele Expression: Recessive genes, often detrimental, become expressed due to a higher chance of inheriting identical copies from both parents.
  • Loss of Heterozygosity: Reduces genetic variation within the population, making it more vulnerable to diseases and environmental changes.
  • Inbreeding Depression: A general decline in fitness due to the expression of deleterious recessive alleles.

Phenotypic Consequences of Inbreeding

The genetic consequences translate into observable phenotypic effects. These effects are collectively known as inbreeding depression and can impact various aspects of animal health and productivity.

  • Reduced Fertility: Inbred animals often exhibit lower fertility rates, including decreased sperm viability in males and reduced ovulation rates in females.
  • Increased Susceptibility to Diseases: A weakened immune system makes inbred animals more prone to infections and diseases.
  • Reduced Growth Rate: Inbreeding can negatively impact growth rates and overall body size.
  • Congenital Defects: Increased incidence of birth defects and abnormalities.
  • Reduced Milk Production (in Dairy Animals): A classic example of inbreeding depression is the decline in milk yield observed in some dairy breeds.
Consequence Genetic Basis Phenotypic Manifestation
Reduced Fertility Exposure of recessive infertility genes Lower conception rates, reduced sperm viability
Increased Disease Susceptibility Loss of heterozygosity affecting immune response Higher incidence of infections
Reduced Growth Rate Expression of recessive growth-inhibiting alleles Smaller body size, slower development

Mitigation Strategies

To counter the negative effects of inbreeding, breeders often employ strategies such as:

  • Outcrossing: Mating with unrelated individuals from different populations.
  • Crossbreeding: Mating individuals from different breeds to introduce new genetic material.
  • Genetic Screening: Identifying and eliminating carriers of deleterious recessive alleles.

Conclusion

Inbreeding, while potentially useful for trait fixation, carries significant genetic and phenotypic risks, primarily manifesting as inbreeding depression. Careful planning, incorporating outcrossing and genetic screening, is crucial for maintaining the health, productivity, and genetic diversity of animal populations. The NDDB and other organizations are actively promoting responsible breeding practices to minimize the detrimental effects of inbreeding and ensure sustainable livestock production.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Inbreeding Coefficient (F)
The probability that an allele in an individual is inherited from both parents who are related.
Outcrossing
Mating of individuals that are not closely related, often from different populations, to increase genetic diversity.

Key Statistics

Inbreeding depression can reduce milk yield in dairy cattle by up to 10-20% in severe cases (NDDB data, knowledge cutoff).

Source: NDDB (National Dairy Development Board)

The average inbreeding coefficient in some livestock breeds can reach 0.5 or higher if unchecked (Source: FAO – Knowledge Cutoff).

Source: FAO (Food and Agriculture Organization)

Examples

Holstein-Friesian Breed

The Holstein-Friesian breed, known for its high milk production, has experienced periods of inbreeding depression, prompting breeding programs to incorporate outcrossing strategies.

Frequently Asked Questions

Why is inbreeding sometimes used in animal breeding?

Inbreeding is used to fix desirable traits and create more uniform populations, but it must be carefully managed to avoid inbreeding depression.

Topics Covered

Animal GeneticsAnimal BreedingInbreeding DepressionGenetic VariationSelective Breeding