UPSC MainsMEDICAL-SCIENCE-PAPER-I202415 Marks
Q6.

Thyroid Gland: Anatomy & Surgical Aspects

A middle-aged female notices a lump in the midline of the neck. She notices it moves with swallowing. The surgeon gives a tentative diagnosis of goitre. Describe the thyroid gland under the following headings : (i) Gross anatomy and relations (ii) Blood supply and lymphatic drainage (iii) Surgical anatomy of thyroid gland

How to Approach

This question requires a detailed anatomical description of the thyroid gland, focusing on its gross anatomy, relations, blood supply, lymphatic drainage, and surgical considerations. The answer should be structured logically, covering each aspect systematically. Diagrams, while not possible in this text-based format, should be mentally visualized while answering. Emphasis should be placed on clinically relevant anatomical landmarks crucial for surgical intervention. A clear understanding of the recurrent laryngeal nerve and parathyroid glands is essential for the surgical anatomy section.

Model Answer

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Introduction

The thyroid gland, a vital component of the endocrine system, plays a crucial role in regulating metabolism. Its anatomical location in the anterior neck makes it susceptible to palpable abnormalities like goitres, as presented in the clinical scenario. A thorough understanding of its anatomy is paramount for accurate diagnosis, surgical planning, and minimizing iatrogenic complications. The thyroid gland is unique in its butterfly shape and its close relationship with vital structures in the neck, necessitating a detailed knowledge of its gross anatomy, vascular supply, lymphatic drainage, and surgical landmarks.

(i) Gross Anatomy and Relations

The thyroid gland is a reddish-brown, butterfly-shaped endocrine gland located in the anterior neck. It consists of two lobes, connected by a narrow isthmus that often overlies the second and third tracheal rings.

  • Lobes: Each lobe is approximately 5-6 cm long, 2-3 cm wide, and 1-2 cm thick. They extend from the cricoid cartilage to the level of the thyroid cartilage.
  • Isthmus: The isthmus is typically 1-2 cm in width and connects the two lobes.
  • Capsule: The gland is enclosed in a fibrous capsule from which septa extend into the parenchyma.
  • Pyramidal Lobe: Present in approximately 30-60% of individuals, it extends upwards from the isthmus to the hyoid bone.

Relations:

The thyroid gland has important relations anteriorly, posteriorly, and laterally:

  • Anteriorly: Skin, superficial fascia, platysma, strap muscles (sternohyoid and sternothyroid).
  • Posteriorly: Pretracheal fascia, trachea, esophagus, recurrent laryngeal nerves, inferior thyroid artery, and parathyroid glands.
  • Laterally: Carotid sheath containing the common carotid artery, internal jugular vein, and vagus nerve.

(ii) Blood Supply and Lymphatic Drainage

Blood Supply:

The thyroid gland has a rich blood supply, receiving arterial blood from the superior and inferior thyroid arteries.

  • Superior Thyroid Artery: A branch of the external carotid artery, it supplies the upper part of the lobes.
  • Inferior Thyroid Artery: Usually arises directly from the subclavian artery, it supplies the lower part of the lobes.
  • Thyroidea Ima Artery: Present in approximately 25% of individuals, it arises from the brachiocephalic trunk and supplies the isthmus.

Venous Drainage:

Venous drainage occurs via the superior, middle, and inferior thyroid veins.

  • Superior Thyroid Vein: Drains into the internal jugular vein.
  • Middle Thyroid Vein: Drains into the internal jugular vein.
  • Inferior Thyroid Vein: Drains into the brachiocephalic vein.

Lymphatic Drainage:

Lymphatic drainage follows the blood vessels and drains into pretracheal, pretracheal, and paratracheal lymph nodes.

  • Pretracheal Nodes: Located anterior to the trachea.
  • Paratracheal Nodes: Located alongside the trachea.
  • Delphian Node: Located at the junction of the two lobes.

(iii) Surgical Anatomy of Thyroid Gland

Surgical anatomy focuses on structures at risk during thyroid surgery, primarily the recurrent laryngeal nerve and the parathyroid glands.

  • Recurrent Laryngeal Nerve (RLN): This branch of the vagus nerve innervates most of the intrinsic muscles of the larynx, crucial for voice production. Its course is variable but consistently lies in the tracheoesophageal groove. Injury to the RLN can cause vocal cord paralysis.
  • External Branch of Superior Laryngeal Nerve (EBSLN): Supplies the cricothyroid muscle, important for voice pitch. It is at risk during superior pole thyroidectomy.
  • Parathyroid Glands: Typically four small glands located on the posterior surface of the thyroid gland. They regulate calcium homeostasis. Careful identification and preservation of the parathyroid glands are crucial to prevent hypocalcemia.

Important Landmarks: The cricoid cartilage, the trachea, and the carotid sheath serve as important landmarks during thyroid surgery. Ligament of Berry (a fibrous band connecting the cricoid cartilage and the first tracheal ring) is also a key landmark.

Surgical Approaches: Various surgical approaches exist, including transverse cervical incision, oblique incision, and anterior mediastinal approach (for substernal goiters). The choice of approach depends on the size and location of the goitre.

Conclusion

In conclusion, a comprehensive understanding of the thyroid gland’s anatomy – its gross structure, vascular supply, lymphatic drainage, and crucially, its surgical relationships – is essential for clinicians. Accurate diagnosis and safe surgical management of thyroid disorders, such as goitres, rely heavily on this anatomical knowledge. Minimizing complications like vocal cord paralysis and hypocalcemia requires meticulous surgical technique and a thorough appreciation of the gland’s surrounding structures.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Goitre
An abnormal enlargement of the thyroid gland, which can be diffuse or nodular. It can be caused by iodine deficiency, autoimmune disease (Hashimoto's thyroiditis), or other factors.
Hypocalcemia
A condition characterized by abnormally low levels of calcium in the blood, often resulting from damage or removal of the parathyroid glands during thyroid surgery.

Key Statistics

Globally, over 70 million people are estimated to have goitre, with iodine deficiency being a major contributing factor in many regions. (WHO, 2023 - knowledge cutoff)

Source: World Health Organization (WHO)

Post-thyroidectomy hypocalcemia occurs in approximately 1-5% of patients, with the risk being higher in cases of total thyroidectomy or extensive nodal dissection. (American Thyroid Association Guidelines, 2015 - knowledge cutoff)

Source: American Thyroid Association

Examples

Hashimoto's Thyroiditis

An autoimmune disease where the body's immune system attacks the thyroid gland, leading to chronic inflammation and often hypothyroidism. This can result in goitre formation as the gland attempts to compensate.

Frequently Asked Questions

What is the clinical significance of the Delphian node?

The Delphian node is often the first site of lymphatic spread in thyroid cancer. Therefore, its careful assessment during surgery is crucial for staging and prognosis.

Topics Covered

AnatomySurgeryEndocrinologyEndocrine SystemNeck AnatomySurgical Anatomy