UPSC Mains ZOOLOGY-PAPER-II 2025

32 Questions • 400 Marks • With Detailed Model Answers

1
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

1.(a) Protein sorting in Golgi apparatus

Cell BiologyMolecular Biology
2
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

1.(b) Structure and function of Lampbrush chromosome

Cell BiologyGenetics
3
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

1.(c) Symptoms, causes and treatment of thalassemia

Human PhysiologyGenetics
4
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

1.(d) Coupling and repulsion phases of linkage

Genetics
5
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

1.(e) Sympatric and allopatric speciation

Evolution
6
10 Markseasy

2.(a)(i) Describe composition of plasma membrane.

Cell Biology
7
10 Marksmedium

2.(a)(ii) Differentiate between facilitated and passive diffusion across the membrane with examples.

Cell BiologyPhysiology
8
15 Markshard

2.(b) Explain how mutations affect variations in population and natural selection.

EvolutionGenetics
9
15 Marksmedium

2.(c) Draw pedigrees for autosomal recessive and sex-linked inheritance using examples from human.

Genetics
10
10 Marksmedium

3.(a)(i) Describe the synthetic theory of evolution.

Evolution
11
10 Marksmedium

3.(a)(ii) Describe common types of mimicry in insects with suitable examples.

EcologyAnimal Behavior
12
15 Markshard

3.(b) Discuss the process of chain elongation during protein synthesis in prokaryotes.

Molecular BiologyBiochemistry
13
15 Markshard

3.(c) Describe the mechanism of ribozyme action and comment on its technological applications.

BiochemistryMolecular Biology
14
20 Markshard

4.(a) Describe the steps of constructing a recombinant DNA and its cloning.

BiotechnologyMolecular Biology
15
15 Marksmedium

4.(b) Discuss the major morphological modifications during horse evolution.

EvolutionPaleontology
16
15 Markseasy

4.(c) Write down the salient features of zoological nomenclature.

TaxonomySystematics
17
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

5.(a) Block to polyspermy

Reproductive BiologyDevelopmental Biology
18
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

5.(b) Fate map of frog embryo

Developmental BiologyEmbryology
19
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

5.(c) Activation energy based mechanism of enzyme action

BiochemistryEnzymology
20
10 Marks150 Wordseasy

Write on the following in about 150 words each:

5.(d) Structure of dipeptide unit of a protein

BiochemistryMolecular Biology
21
10 Marks150 Wordsmedium

Write on the following in about 150 words each:

5.(e) Transmission of nerve impulse through synapse

NeurobiologyPhysiology
22
10 Marksmedium

6.(a)(i) Write down the reactions that produce NADH during Krebs cycle.

BiochemistryCellular Respiration
23
10 Marksmedium

6.(a)(ii) Explain the role of proton gradient in oxidative ATP synthesis.

BiochemistryCellular Respiration
24
15 Marksmedium

6.(b) Describe characteristic features and specific functions of lymphocytes, monocytes and neutrophils.

ImmunologyHematology
25
15 Markshard

6.(c) Diagrammatically describe the steps of development of heart in mammals.

Developmental BiologyEmbryology
26
10 Marksmedium

7.(a)(i) Explain sigmoidal nature of oxygen dissociation curve for hemoglobin.

PhysiologyBiochemistry
27
10 Marksmedium

7.(a)(ii) Describe differences between adult and fetal hemoglobin and comment on their physiological significance.

PhysiologyBiochemistry
28
15 Markshard

7.(b) Discuss the mechanism of action of cytotoxic-T cell.

Immunology
29
15 Markshard

7.(c) What are homeotic genes ? Explain their role in body axis formation in chick.

Developmental BiologyGenetics
30
20 Markshard

8.(a) Describe the stages of fertilization in chick with diagram.

Reproductive BiologyDevelopmental Biology
31
15 Marksmedium

8.(b) Draw structure of cholesterol and explain its role in health and diseases.

BiochemistryHuman Physiology
32
15 Marksmedium

8.(c) Discuss the role of ovarian hormones in female reproduction.

Reproductive BiologyEndocrinology