UPSC MainsAGRICULTURE-PAPER-I201410 Marks150 Words
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Q20.

Show full reactions where (i) Alcohol dehydrogenase, (ii) Nitrate reductase, (iii) Glucokinase and (iv) Succinate dehydrogenase are involved, therewith mentioning respective co-factor, co-enzyme, prosthetic group etc., if so required.

How to Approach

This question requires a detailed understanding of enzyme mechanisms in plant metabolism. The approach should be to first briefly introduce each enzyme, then outline the full reaction it catalyzes, and finally, meticulously list the cofactors/coenzymes/prosthetic groups involved. A tabular format might be beneficial to present the information clearly and concisely. Emphasis should be placed on accuracy and completeness regarding the biochemical details. The answer must demonstrate knowledge of core plant metabolic pathways.

Model Answer

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Introduction

Enzymes are biological catalysts crucial for facilitating biochemical reactions within plant cells. They exhibit remarkable specificity and efficiency. This question delves into the reaction mechanisms of four key enzymes involved in plant metabolism: Alcohol dehydrogenase (ADH), Nitrate reductase (NR), Glucokinase (GK), and Succinate dehydrogenase (SDH). Understanding these enzymatic pathways is fundamental to comprehending plant processes like respiration, nitrogen assimilation, and carbohydrate metabolism. These enzymes showcase the intricate interplay of cofactors, coenzymes, and prosthetic groups vital for their catalytic activity.

Alcohol Dehydrogenase (ADH)

ADH catalyzes the reversible interconversion of alcohols and aldehydes or ketones. It's crucial in ethanol fermentation and detoxification of alcohols.

Reaction: CH3CH2OH + NAD+ ⇌ CH3CHO + NADH + H+

Cofactor/Coenzyme: Nicotinamide adenine dinucleotide (NAD+/NADH) - acts as a hydrogen acceptor.

Nitrate Reductase (NR)

NR is a vital enzyme in the nitrogen assimilation pathway, converting nitrate (NO3-) to nitrite (NO2-), a precursor to ammonia.

Reaction: NO3- + NADH + H+ ⇌ NO2- + NAD+ + H2O

Cofactors/Coenzymes: NADH (nicotinamide adenine dinucleotide) – electron donor, FAD (flavin adenine dinucleotide) - prosthetic group bound to the enzyme.

Glucokinase (GK)

GK, also known as hexokinase, phosphorylates glucose to glucose-6-phosphate. It plays a critical role in glucose metabolism and regulation of plant growth and development.

Reaction: Glucose + ATP ⇌ Glucose-6-Phosphate + ADP

Cofactor: Magnesium ions (Mg2+) – essential for ATP binding and catalysis.

Succinate Dehydrogenase (SDH)

SDH is a complex enzyme involved in both the citric acid cycle and the electron transport chain. It catalyzes the oxidation of succinate to fumarate.

Reaction: Succinate + GDP + FAD ⇌ Fumarate + GTP + FADH2

Cofactors/Coenzymes/Prosthetic Groups: GDP (guanosine diphosphate), FAD (flavin adenine dinucleotide), Iron-sulfur (Fe-S) clusters (multiple – Fe4S4, Fe3S4, Fe-S) – involved in electron transfer.

Enzyme Reaction Cofactor/Coenzyme/Prosthetic Group
ADH Alcohol ↔ Aldehyde/Ketone NAD+/NADH
NR Nitrate ↔ Nitrite NADH, FAD
GK Glucose ↔ Glucose-6-Phosphate Mg2+
SDH Succinate ↔ Fumarate GDP, FAD, Fe-S clusters

Conclusion

The enzymatic reactions detailed above highlight the intricate biochemical machinery within plants. Each enzyme plays a critical role in specific metabolic pathways, and their function is intricately linked to the presence of necessary cofactors and prosthetic groups. A thorough understanding of these enzymatic processes is essential for comprehending plant physiology and for developing strategies to improve crop yields and resilience in a changing climate. Further research into these enzymes can unlock new avenues for biotechnological applications.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Cofactor
A non-protein chemical compound that is required for the biological activity of an enzyme.
Prosthetic Group
A non-protein component tightly bound to an enzyme and essential for its activity. Unlike cofactors, prosthetic groups are permanently attached to the enzyme.

Key Statistics

Nitrate reductase activity is often limiting in nitrogen assimilation, and its efficiency is influenced by environmental factors like light and temperature. Studies show a 20-30% increase in NR activity under optimal light conditions (Source: Plant Physiology, 2018).

Source: Plant Physiology, 2018

Glucokinase plays a role in regulating starch biosynthesis. In some plants, GK activity can increase up to 5-fold during periods of high glucose availability (Source: Journal of Experimental Botany, 2020).

Source: Journal of Experimental Botany, 2020

Examples

Ethanol Production in Yeast

Alcohol dehydrogenase is crucial in the fermentation process used by yeast (Saccharomyces cerevisiae) to produce ethanol from sugars. This process is widely utilized in the biofuel industry.

Nitrogen Fixation in Legumes

Nitrate reductase is essential in legumes, which can fix atmospheric nitrogen, converting it into usable forms for plant growth. This symbiotic relationship reduces the need for synthetic nitrogen fertilizers.

Frequently Asked Questions

What is the difference between a cofactor and a prosthetic group?

A cofactor is a loosely bound molecule required for enzyme activity, whereas a prosthetic group is a tightly bound molecule that is permanently associated with the enzyme.

Why are cofactors important for enzyme function?

Cofactors often participate directly in the catalytic reaction, acting as electron carriers, stabilizing the enzyme structure, or facilitating substrate binding.

Topics Covered

BotanyBiochemistryPlant PhysiologyEnzymologyMetabolism