UPSC Mains MEDICAL-SCIENCE-PAPER-II 2018

Enumerate the causes of acute hepatitis.

What are the natural history and clinical manifestations of chronic hepatitis-C infection?

What are the direct acting antiviral agents for hepatitis-C infection?

A 10-month-old infant with "Tetralogy of Fallot" is brought to the paediatric emergency ward with history of excessive crying and then becoming dyspneic, drowsy and bluish.

What is the likely diagnosis in this infant? Mention the basis for diagnosis.

Describe the management of this condition.

Describe the aetio-pathogenesis, clinical features and management of "Bipolar Disorder".

Enumerate the side effects of commonly used anti-psychotic drugs.

A 16-month-old child attending Paediatrics OPD with past history of diarrhoea and respiratory infections was found to have loss of subcutaneous fat and weight of 5.5 kilograms.

Which physical examination findings would help you to arrive at diagnosis in this child?

Describe the two phases of treatment for this condition.

How does Classical scabies differ from "Crusted" scabies infection?

How do you treat "Crusted" scabies infection in an institution?

A middle-aged hypothyroid woman on irregular medication became drowsy two days ago following an episode of fever.

What could be the causes of drowsiness in this patient?

How will you diagnose and manage the patient?

State cardio-vascular manifestations in hypothyroidism.

A 10-month-old infant having watery nasal discharge for the last 2 days developed rapid breathing, chest retraction and decreased feeding over the last one day.

What is the likely diagnosis in this patient?

Enumerate the microbiological agents for this condition.

Discuss the investigations and management of this condition.

Describe various theories which have been proposed to explain the pathogenesis of vitiligo.

How do you assess the severity of vitiligo?

Describe the lines of treatment of various grades of the disease.

A young male patient came to the medical emergency department with fever, headache and recurrent vomiting. He was also having some skin lesions on both lower limbs and abdomen. On clinical examination, he was drowsy and having neck rigidity.

What is his differential diagnosis?

Discuss in brief the clinical manifestations, diagnosis and management of acute meningitis.

What are the causes of recurrent meningitis?

A 32-week preterm neonate born by a Caesarian section is found to have a respiratory rate of 70/minute, grunting and cyanosis within half an hour of birth.

What is the most likely diagnosis in this neonate?

Describe the management of this condition.

Write about its important complications.

A young woman presented to the emergency department with a history of pesticide intake. She has massive frothing from the mouth and nose.

Which is the pesticide she is likely to have consumed?

State what would be the clinical features and management in this patient.

Define the "Intermediate Syndrome" which may occur in this setting and its management.