UPSC MainsANI-HUSB-VETER-SCIENCE-PAPER-II201910 Marks150 Words
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Q16.

Emerging zoonotic diseases of International concern with specific remarks on prevalence, control and preventive measures for Influenza.

How to Approach

This question requires a structured response focusing on Influenza as a key emerging zoonotic disease. The approach should involve defining zoonotic diseases and influenza, briefly outlining its prevalence globally, detailing control measures (surveillance, diagnostics, vaccines), and preventive strategies (biosecurity, public health education). A table summarizing different influenza strains and their characteristics could be beneficial. Finally, highlighting the 'One Health' approach is crucial. A word limit of 150 demands conciseness and prioritization of key information.

Model Answer

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Introduction

Zoonotic diseases, illnesses transmitted from animals to humans, are a growing global health concern, exacerbated by climate change, deforestation, and increased human-animal interaction. Influenza, a highly contagious viral respiratory illness, exemplifies this threat. The recent COVID-19 pandemic underscored the devastating consequences of emerging zoonoses. Influenza viruses, capable of undergoing antigenic drift and shift, pose a constant risk of pandemics, necessitating robust surveillance and preventative measures. This response will address the prevalence, control, and prevention of influenza, a significant emerging zoonotic disease.

Understanding Influenza as a Zoonotic Disease

Influenza viruses are classified into types A, B, C, and D. While types C and D primarily infect animals, types A and B affect humans. Influenza A viruses, particularly, are notorious for their zoonotic potential, circulating in various animal reservoirs like wild birds (natural host), pigs, and occasionally other mammals. The 'Spanish Flu' (1918) and the 'Swine Flu' (H1N1, 2009) are stark reminders of pandemic potential.

Prevalence and Global Distribution

Influenza prevalence varies seasonally, with peaks during winter months. According to the World Health Organization (WHO), seasonal influenza causes an estimated 290,000 to 500,000 respiratory deaths globally each year. The emergence of novel influenza strains, like H5N1 (avian influenza) and H7N9, poses significant pandemic risks. Africa and Southeast Asia are particularly vulnerable due to close human-animal contact and limited healthcare infrastructure.

Control Measures

  • Surveillance: Global influenza surveillance networks, coordinated by WHO, monitor viral evolution and identify potential pandemic strains. The Global Influenza Surveillance and Response System (GISRS) plays a crucial role.
  • Diagnostics: Rapid and accurate diagnostic tests (RT-PCR) are essential for timely identification and isolation of infected individuals.
  • Vaccines: Annual influenza vaccines are developed based on predicted circulating strains. Vaccine effectiveness varies and requires continuous adaptation.
  • Antiviral Medications: Drugs like Oseltamivir and Zanamivir can reduce the severity and duration of influenza infection.

Preventive Measures

Preventive measures encompass both individual and public health approaches:

  • Biosecurity: Strict biosecurity measures in poultry farms and livestock facilities are critical to prevent virus transmission.
  • Public Health Education: Raising awareness about proper hygiene practices (handwashing, respiratory etiquette) and safe food handling is essential.
  • 'One Health' Approach: Recognizing the interconnectedness of human, animal, and environmental health is crucial. Collaboration between veterinary, public health, and environmental sectors is vital.
  • Movement Restrictions: In case of outbreaks, restricting movement of animals and people can help contain the spread.
Influenza Strain Primary Reservoir Human Impact
H1N1 Swine 2009 Pandemic, Seasonal Flu
H5N1 Wild Birds High Mortality in Humans
H7N9 Birds Localized Outbreaks in Humans

Challenges and Future Directions

The rapid mutation rate of influenza viruses and the emergence of drug-resistant strains pose ongoing challenges. Research on broadly neutralizing antibodies and universal influenza vaccines is crucial for long-term pandemic preparedness. Improved global cooperation and capacity building are essential for effective surveillance and response.

Conclusion

Emerging zoonotic diseases like influenza necessitate a proactive and collaborative approach. Effective control relies on robust surveillance systems, rapid diagnostics, and adaptable vaccines. The 'One Health' framework, integrating human, animal, and environmental health, is paramount. Continued investment in research, particularly focused on universal vaccines and improved diagnostic tools, is vital to mitigate the risk of future influenza pandemics and strengthen global health security.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Zoonosis
A zoonosis is a disease that is naturally transmitted from animals to humans. It can be bacterial, viral, fungal, parasitic, or helminthic.
Antigenic Shift
A major genetic change in influenza viruses, resulting from the reassortment of genetic material between different influenza strains. This can lead to the emergence of entirely new subtypes.

Key Statistics

Seasonal influenza causes an estimated 290,000 to 500,000 respiratory deaths globally each year (WHO, 2019).

Source: World Health Organization (WHO)

The GISRS network comprises 150 laboratories in 118 countries, providing critical data for global influenza surveillance (WHO, 2023).

Source: World Health Organization (WHO)

Examples

The 1918 Spanish Flu Pandemic

The 1918 Spanish Flu pandemic, caused by an H1N1 influenza A virus, infected an estimated 500 million people worldwide and resulted in 50-100 million deaths, demonstrating the devastating potential of influenza.

Frequently Asked Questions

Why are influenza viruses so prone to mutation?

Influenza viruses have a high mutation rate due to the lack of proofreading mechanisms in their RNA polymerase. This leads to frequent errors during replication, resulting in antigenic drift and shift.

Topics Covered

Veterinary Public HealthEpidemiologyZoonosesInfluenzaDisease Control