UPSC Mains MEDICAL-SCIENCE-PAPER-I 2011

Describe the nerve supply of tongue correlating it with its development. Add a note on its Blood supply and lymphatic drainage along with applied anatomy.

Define porto caval anastomosis. What are their sites ? Write also the anastomosing vessels on each site with its applied anatomy.

Define Jaundice. Write briefly about formation and fate of bilirubin. Give the major differences between the three types of Jaundice.

Define Blood Pressure. Enumerate the various factors affecting the blood pressure. How is the blood pressure regulated in the long term ?

Give the role of a micronutrient as a component of 'glucose tolerance factor'. What is its RDA and deficiency manifestation ?

What are the tests based on the intermediary metabolic functions of liver ? Explain the basis of each of these tests.

Describe venous drainage of lower limb and its applied anatomy.

Discuss relations and supports of uterus. Add a note on its applied anatomy.

Describe Carpal tunnel syndrome, its manifestations and the causes.

Name the contractile proteins in skeletal muscle. What is the electron microscopic appearance of muscle ? Write sequence of events in muscular contraction.

Discuss in short the structure and sequence of events at neuromuscular junction during nerve impulse transmission. Add a note on myasthenia gravis.

What are the growth curves of various body organs after birth? Enumerate the various factors affecting growth. Discuss briefly clinical abnormalities related to growth.

Write about the tests which indicate that the female is ovulating.

Explain the effect of anticonvulsant drugs (Phenobarbital/diphenylhydantoin) on the vitamin requirements in the body. State the role that the relevant vitamin/vitamins play(s) in the human body.

Outline the components of the translation apparatus in eukaryotes.

What could be the nutritional deficiencies encountered in an 'Alcoholic' person ? Explain the reasons clearly.

Enumerate the various etiological agents causing neoplasia. Discuss the mechanism of viral carcinogenesis.

What is the mechanism involved in Type I hypersensitivity reaction ? What types of agents can induce it ? Describe the laboratory evaluation and management of allergic reactions.

Classify antimalarial drugs. Discuss the common side effects of chloroquine administration. What are the other therapeutic uses of chloroquine ?

A 50-year male has been found hanged in a bath-room along with incised wound on wrist, groin and cubital region. How will you establish cause of death and opine whether he has expired of hanging or injuries sustained ?

What is the role of genetic marker in diagnosis of Chronic Myeloid Leukemia (CML) ? Give clinical features and blood picture of CML.

Enumerate the important parasitic and fungal opportunistic infections which can occur during the course of HIV infection. Discuss the current strategies of HIV testing and to monitor the progress of HIV infection. Write briefly the recommended treatment.