UPSC MainsMEDICAL-SCIENCE-PAPER-I201115 Marks
हिंदी में पढ़ें
Q9.

Describe Carpal tunnel syndrome, its manifestations and the causes.

How to Approach

This question requires a detailed understanding of Carpal Tunnel Syndrome (CTS). The answer should begin with a clear definition, followed by a comprehensive discussion of its manifestations (signs and symptoms) and the underlying causes. A structured approach, categorizing causes into intrinsic and extrinsic factors, will be beneficial. Mentioning diagnostic methods and potential complications will add depth. The answer should demonstrate medical knowledge and clarity.

Model Answer

0 min read

Introduction

Carpal Tunnel Syndrome (CTS) is a common entrapment neuropathy affecting the median nerve as it passes through the carpal tunnel in the wrist. Characterized by pain, numbness, tingling, and weakness in the hand and fingers, CTS significantly impacts daily activities and quality of life. The prevalence of CTS is increasing, likely due to repetitive strain injuries associated with modern work and lifestyle. Understanding its pathophysiology, clinical presentation, and etiology is crucial for effective diagnosis and management. This answer will detail the manifestations and causes of Carpal Tunnel Syndrome.

Understanding Carpal Tunnel Syndrome

The carpal tunnel is a narrow passageway on the palmar side of the wrist formed by the carpal bones and the transverse carpal ligament. Within this tunnel lie the median nerve, along with tendons that flex the fingers. Compression of the median nerve within this space leads to CTS.

Manifestations of Carpal Tunnel Syndrome

The symptoms of CTS typically develop gradually and can vary in severity. They often begin insidiously and may be intermittent initially.

  • Sensory Symptoms: These are the earliest and most common symptoms. They include:
    • Numbness and tingling in the thumb, index, middle, and radial half of the ring finger.
    • Pain radiating up the forearm.
    • Burning sensation in the hand.
    • Increased symptoms at night, often disrupting sleep.
  • Motor Symptoms: As the condition progresses, motor weakness may develop.
    • Weakness in the thenar muscles (muscles at the base of the thumb), leading to difficulty with grip strength and fine motor movements.
    • Clumsiness and dropping objects.
    • Atrophy of the thenar muscles in severe, long-standing cases.
  • Vascular Symptoms: Some patients report changes in hand temperature, color, and swelling, though these are less common.

Causes of Carpal Tunnel Syndrome

The causes of CTS are multifactorial, often involving a combination of predisposing factors and aggravating influences. These can be broadly categorized into intrinsic and extrinsic causes.

Intrinsic Causes (Factors within the individual)

  • Anatomy: A smaller carpal tunnel, inherited anatomical variations, or wrist fractures can predispose individuals to CTS.
  • Age: The risk of CTS increases with age, potentially due to age-related changes in the tendons and ligaments.
  • Sex: Women are more likely to develop CTS than men, possibly due to a smaller carpal tunnel and hormonal influences.
  • Medical Conditions: Certain medical conditions are associated with an increased risk of CTS:
    • Diabetes: Diabetic neuropathy can affect the median nerve.
    • Hypothyroidism: Can cause fluid retention and nerve compression.
    • Rheumatoid Arthritis: Inflammation can narrow the carpal tunnel.
    • Pregnancy: Hormonal changes and fluid retention during pregnancy can contribute to CTS.
    • Obesity: Increased body mass index is associated with a higher risk.
  • Genetic Predisposition: Family history of CTS can increase susceptibility.

Extrinsic Causes (Factors related to activities and environment)

  • Repetitive Hand Movements: Activities involving repetitive wrist flexion, extension, or vibration can contribute to CTS. Examples include:
    • Assembly line work
    • Typing
    • Using hand tools
    • Playing musical instruments
  • Forceful Gripping: Jobs requiring forceful gripping or prolonged use of vibrating tools.
  • Wrist Position: Maintaining the wrist in an awkward position for extended periods.
  • Trauma: Wrist fractures or dislocations can damage the carpal tunnel.

Diagnosis

Diagnosis typically involves a combination of clinical evaluation, physical examination, and electrodiagnostic studies.

  • Tinel's Sign: Tapping over the median nerve at the wrist elicits tingling.
  • Phalen's Test: Holding the wrists in full flexion for 60 seconds reproduces symptoms.
  • Nerve Conduction Studies (NCS): Measures the speed of electrical signals along the median nerve.
  • Electromyography (EMG): Assesses the electrical activity of muscles controlled by the median nerve.

Conclusion

Carpal Tunnel Syndrome is a prevalent condition resulting from median nerve compression, manifesting as sensory and motor deficits in the hand. Its etiology is complex, involving both intrinsic and extrinsic factors. Early diagnosis through clinical evaluation and electrodiagnostic studies is crucial for initiating appropriate treatment, ranging from conservative measures like splinting and activity modification to surgical intervention in severe cases. Preventive strategies focusing on ergonomic principles and addressing underlying medical conditions are essential for reducing the incidence of CTS.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Entrapment Neuropathy
A condition caused by compression of a peripheral nerve, leading to pain, numbness, tingling, and weakness in the area supplied by the nerve.
Thenar Eminence
The fleshy eminence on the palm of the hand at the base of the thumb, formed by the thenar muscles. Atrophy of this eminence is a sign of chronic CTS.

Key Statistics

Approximately 5% of adults are affected by Carpal Tunnel Syndrome. (Source: National Institute of Neurological Disorders and Stroke, NIH - Knowledge Cutoff 2023)

Source: National Institute of Neurological Disorders and Stroke, NIH

Women are 3-5 times more likely to develop CTS than men. (Source: American Academy of Orthopaedic Surgeons - Knowledge Cutoff 2023)

Source: American Academy of Orthopaedic Surgeons

Examples

Assembly Line Worker

A worker on an automotive assembly line repeatedly performs the same hand movements for hours each day, leading to inflammation and compression of the median nerve, ultimately resulting in CTS.

Frequently Asked Questions

Can Carpal Tunnel Syndrome resolve on its own?

Mild cases of CTS may improve with conservative treatment and lifestyle modifications. However, without intervention, the condition often progresses, and symptoms can become chronic and debilitating.

Topics Covered

NeurologyOrthopedicsPeripheral NerveCarpal TunnelHand