UPSC MainsMEDICAL-SCIENCE-PAPER-II2025 Marks
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Q10.

How do you classify eczema?

How to Approach

To classify eczema effectively, the answer should begin with a clear definition of eczema. The core of the answer will involve detailing the various types of eczema, using a classification system that is both comprehensive and easy to understand. For each type, key characteristics, causes (if known), and affected areas should be highlighted. A tabular format can be particularly useful for presenting the distinct features of different eczema types. The conclusion should summarize the complexity of eczema and the importance of accurate diagnosis.

Model Answer

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Introduction

Eczema, also known as dermatitis, is a broad term encompassing a group of inflammatory skin conditions characterized by symptoms such as dryness, itching, redness, swelling, and sometimes oozing or blistering. It is not a single disease but rather a clinical syndrome resulting from impaired skin barrier function and abnormal immune responses. While the exact cause often remains unclear, it is generally believed to stem from a combination of genetic predispositions, environmental triggers, and immune system dysregulation. Understanding the classification of eczema is crucial for accurate diagnosis, effective management, and tailored treatment strategies, given the varied etiologies and presentations of these conditions.

Eczema can be classified in several ways, often based on its underlying causes, clinical presentation, or location. However, a common and clinically useful classification categorizes eczema into several distinct types, each with its own characteristic features. It is important to note that different types of eczema can sometimes overlap or co-exist in an individual.

Major Types of Eczema

The seven most commonly recognized types of eczema are:

  • Atopic Dermatitis (Atopic Eczema): This is the most prevalent and chronic form of eczema, often beginning in infancy or early childhood. It is characterized by dry, intensely itchy patches of skin that can crack, ooze, or form crusts. Atopic dermatitis is strongly linked to a genetic predisposition and often occurs alongside other allergic conditions like asthma and allergic rhinitis (hay fever).
  • Contact Dermatitis: This type develops when the skin comes into direct contact with a substance that causes either irritation or an allergic reaction.
    • Irritant Contact Dermatitis (ICD): Caused by direct damage to the skin from irritants like harsh soaps, chemicals, or prolonged exposure to water.
    • Allergic Contact Dermatitis (ACD): An immune-mediated, delayed hypersensitivity reaction triggered by allergens such as nickel, certain cosmetics, or poison ivy.
  • Dyshidrotic Eczema (Pompholyx): This type is characterized by small, intensely itchy blisters that typically appear on the palms of the hands, soles of the feet, and sides of the fingers and toes. It is often linked to stress, allergies, or exposure to certain metals.
  • Neurodermatitis (Lichen Simplex Chronicus): This is characterized by localized, intensely itchy patches of thickened, leathery skin. It develops from a cycle of scratching and rubbing in a particular area, often due to an underlying itch sensation, stress, or other dermatological conditions.
  • Nummular Eczema (Discoid Eczema): Characterized by coin-shaped or oval patches of irritated, itchy skin, which can be crusty or scaly. These patches can appear anywhere on the body but are commonly found on the arms, legs, and trunk.
  • Seborrheic Dermatitis: This primarily affects areas of the body with a high concentration of sebaceous (oil) glands, such as the scalp, face (especially around the nose and eyebrows), and chest. It manifests as red, greasy, scaly patches and is a common cause of dandruff.
  • Stasis Dermatitis: This type occurs on the lower legs and is typically associated with poor circulation, often seen in individuals with venous insufficiency, varicose veins, or swelling. Symptoms include redness, itching, scaling, and skin discoloration, often brownish.

Classification of Eczema

Here's a detailed classification table summarizing the key characteristics of each type:

Type of Eczema Key Characteristics Common Locations Primary Causes/Triggers
Atopic Dermatitis Chronic, intensely itchy, dry patches; often red, gray, brown, or purplish depending on skin tone; can ooze/crust. Face, hands, inside elbows, behind knees, generalized. Genetic predisposition, immune system dysfunction, environmental factors (allergens, irritants).
Contact Dermatitis Rash, redness, swelling, itching, sometimes blisters; localized to exposed area. Area of contact with irritant/allergen (e.g., hands, wrists, face). Direct contact with irritants (soaps, chemicals) or allergens (nickel, poison ivy).
Dyshidrotic Eczema Small, clear, intensely itchy blisters; dry, scaly patches when blisters resolve. Palms of hands, soles of feet, sides of fingers/toes. Stress, allergies, sweat, exposure to metals.
Neurodermatitis Thickened, leathery, intensely itchy patches; often single or a few distinct patches. Neck, wrists, ankles, scalp, genital area. Repetitive scratching/rubbing due to underlying itch, stress.
Nummular Eczema Coin-shaped or oval patches; itchy, may ooze or crust. Arms, legs, trunk. Dry skin, skin injury (insect bites), stress.
Seborrheic Dermatitis Red, greasy, scaly patches; flaking (dandruff). Scalp, face (eyebrows, sides of nose), chest, groin. Overgrowth of Malassezia yeast, genetics, stress, hormonal changes.
Stasis Dermatitis Red, itchy, scaly skin on lower legs; swelling, brown discoloration (hyperpigmentation), sometimes ulcers. Lower legs, ankles. Poor blood circulation (venous insufficiency).

While the classification above covers the most common types, other forms or specific manifestations of eczema exist, such as hand eczema (which can be a manifestation of various types), asteatotic eczema (due to extreme dryness), or autoeczematization (an allergic reaction to an infection or inflammation elsewhere on the body).

Conclusion

Eczema represents a complex group of inflammatory skin conditions, broadly classified into distinct types based on their clinical presentation, underlying pathology, and triggers. From the widespread genetic predisposition of atopic dermatitis to the localized reactions of contact dermatitis and the circulatory issues causing stasis dermatitis, each form requires specific diagnostic approaches and management strategies. A comprehensive understanding of these classifications is paramount for dermatologists and healthcare providers to effectively alleviate symptoms, prevent flare-ups, and improve the quality of life for millions affected by these chronic skin conditions.

Answer Length

This is a comprehensive model answer for learning purposes and may exceed the word limit. In the exam, always adhere to the prescribed word count.

Additional Resources

Key Definitions

Eczema
Eczema, also known as dermatitis, is a non-contagious inflammatory skin condition characterized by dryness, redness, itching, and often a rash. It encompasses a group of conditions that weaken the skin's barrier function.
Atopy
Atopy refers to a genetic predisposition to develop allergic hypersensitivity reactions, such as allergic rhinitis (hay fever), asthma, and atopic dermatitis (a common type of eczema).

Key Statistics

Atopic dermatitis affects approximately 10% of adults and 20% of the pediatric population in high-income countries. In India, recent reviews (2011-2021 data) indicate a prevalence ranging from 3.1% to 7.21% among the pediatric population (up to 16 years of age), and 0.98% to 9.2% in studies including both pediatric and adult patients.

Source: De A, Karekar S, Adhav C. Indian J Dermatol. 2023;68(4):487.

A survey among 1,003 Indian parents of children under five years of age reported an Atopic Dermatitis (AD) prevalence of 17.85% (179 cases). This highlights a significant burden of AD in young children in India.

Source: PMC - NIH, "Exploring Atopic Dermatitis in Indian Children: A Comprehensive Survey" (2025-07-30)

Examples

Nickel Allergy

A common example of Allergic Contact Dermatitis is a reaction to nickel, often found in jewelry, belt buckles, or certain electronic devices. Individuals sensitive to nickel may develop an itchy, red rash at the point of skin contact with the metal.

Irritant Contact Dermatitis in Healthcare Workers

Healthcare professionals who frequently wash their hands with harsh soaps and sanitizers, or wear gloves for extended periods, may develop irritant contact dermatitis on their hands due to repeated exposure to irritants and moisture, compromising the skin barrier.

Frequently Asked Questions

Is eczema contagious?

No, eczema is not contagious. It cannot be spread from person to person. It is an inflammatory condition resulting from genetic, environmental, and immune system factors.

Can eczema be cured?

Currently, there is no definitive cure for most types of eczema, particularly chronic conditions like atopic dermatitis. However, symptoms can be effectively managed through various treatments including moisturizers, topical corticosteroids, calcineurin inhibitors, and avoiding triggers. Research is ongoing to find more effective and potentially curative therapies.

Topics Covered

MedicineDermatologySkin DiseasesDermatitis