UPSC Prelims 1999·GS1·science-and-technology·ipr and biotechnology

Which one of the following genetic diseases is sex-linked?

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Last updated 23 May 2026, 3:31 pm IST
  1. ARoyal haemophiliaCorrect
  2. BTay Sachs disease
  3. CCystic fibrosis
  4. DHypertension

Explanation

Royal haemophilia is the correct answer because it is an X linked recessive disorder. This means the gene responsible for the disease is located on the X chromosome. Since males have only one X chromosome, they are more frequently affected by this condition. In contrast, Tay Sachs disease and Cystic fibrosis are autosomal recessive disorders, meaning the defective genes are located on non sex chromosomes. Hypertension is generally considered a lifestyle disease or a complex polygenic trait rather than a single gene sex linked disorder. Therefore, only Royal haemophilia fits the description of a sex linked genetic disease.
science-and-technology: Which one of the following genetic diseases is sex-linked?

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